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The investigational immuno-oncology combination of efti and KEYTRUDA achieved an objective response rate (ORR) of 35.5% (11 of 31 evaluable patients) and a disease control rate (DCR) of 58.1%, according to RECIST 1.1, in 1L HNSCC patients whose tumors do not express PD-L1 (Combined Positive Score [CPS] 20 PD-L1 expression levels are approximately 20%, 30%, and 50% of the HNSCC patient population, respectively

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doi: 10.1016/j.tibs.2015.12.001 34 HaoXRenYFengMWangQWangY